BIO currently quotes at 0.04653, down 6.90%, with a clear bearish technical outlook. On the 15-minute chart, it has been in a continuous downtrend for 64 candles, with the price tightly hugging the downward trendline, indicating strong resistance.

Regarding key levels, 0.04657 serves as an important dynamic resistance and also as a reference point for stop-losses during rebounds. Support below is at 0.04541 (previous low), which is a critical area for continued bearish pressure. Looking upward, resistance levels are sequentially at 0.04842, 0.04887, and 0.04939.

From a trading strategy perspective, caution is advised regarding rebound opportunities. Under the trendline resistance, each rebound could be an entry point for short positions, provided there is no effective breakout. The MACD indicator shows that bullish momentum is clearly waning, which is a warning sign. Close attention should be paid to whether the price will retest the previous low of 0.04541, especially if it breaks below this level, as the risk will further escalate. Overall, short-term vigilance remains necessary.